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In a 52-week study, the Mounjaro 5-mg, 10-mg, and 15-mg doses were compared to titrated Tresiba, a basal insulin, in 1444 adults with type 2 diabetes who were also taking metformin with or without another oral diabetes medication. They had an average starting A1C of 8.1 to 8.2%. At the end of the study, 26% of people on Tresiba met the blood sugar goal (or target). The average daily dose of Tresiba was 49 units per day by the end of the study.
For people taking Mounjaro, their A1C was lowered by 1.9% on the 5-mg dose, 2.0% on the 10-mg dose, and 2.1% on the 15-mg dose. For people taking Tresiba, their A1C was lowered by 1.3%.