Eric Meets the Experts: A Conversation About Mounjaro
00:00-00:04
[Eric Stonestreet and Lilly scientist Tamer Coskun sit on stools facing each other, in front of a brick background.]
CAPTION:
Eric is a patient taking Mounjaro and has type 2 diabetes
Paid Lilly Partnership
[Once weekly Mounjaro (tirzepatide) injection logo appears alongside caption.]
TAMER: Hi Eric. Welcome to Lilly.
ERIC: Thank you. Thank you.
00:04-00:17
[Pans out to reveal Lilly logo in background; Eric Stonestreet and Tamer Coskun continue to converse.]
ERIC: Hey, I’m Eric Stonestreet, and I’m here at Lilly, the makers of Mounjaro. As a paid Lilly partner, I wanted to visit and learn more about this medicine.
TAMER: We are happy to have you here, Eric.
00:17-00:32
[Discussion continues]
CAPTION:
Tamer Coskun
Vice President – Medical
Eli Lilly and Company
TAMER: I’m Tamer Coskun, one of the lead scientists behind Lilly’s Mounjaro. I’ve been here 22 years and was a physician before. What I love about my job is that you have to be curious.
00:33-00:41
[Discussion continues]
TAMER: And also, the other exciting part, you work with the best of the best people.
ERIC: Yeah, like today.
TAMER: Yes, definitely.
ERIC: Yes, perfect.
00:42-00:50
[Discussion continues. Purple bar displaying disclaimer and Once weekly Mounjaro (tirzepatide) injection logo appears.]
TAMER: And especially developing medicine that can help patients like you, and like other people. That’s the most exciting part.
ERIC: Yeah, that must have been quite a ride.
CAPTION:
Mounjaro is a once-weekly injectable prescription medicine for adults with type 2 diabetes used to improve blood sugar along with diet and exercise. Mounjaro is not for use in children.
Continue watching to see Indication and Safety Summary with Warnings.
00:51-01:07
[Discussion continues. Purple bar featuring disclaimers and Mounjaro logo remains.]
ERIC: So, tell me about Mounjaro.
TAMER: Mounjaro works differently by directly activating the receptors of GIP and GLP-1. These are two naturally occurring hormones. Together, these hormones play a role in regulating blood sugar levels in response to eating food.
CAPTION:
DUAL-ACTING GLP-1 + GIP
CAPTION:
Dual-acting Mounjaro is the only FDA-approved type 2 diabetes medicine of its kind. It works differently by directly activating the receptors of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), two naturally occurring hormones.
01:08-01:16
[Discussion continues.]
ERIC: Wow, so this molecule is pretty busy in there doing a lot of stuff. Sounds a lot like… me.
TAMER: Sure.
01:17-01:46
[Discussion continues. Purple bar featuring disclaimers and Mounjaro logo remains. ]
ERIC: Along with diet and exercise, Mounjaro has helped me lower my A1C. How did Mounjaro do in helping others lower their A1C?
TAMER: In studies, up to 90% of those taking Mounjaro reached an A1C under 7%.
ERIC: I didn’t understand the magnitude of type 2 diabetes when I was diagnosed. My doctor, thankfully, woke me up to the fact that I could be doing more. She’s the one who told me about Mounjaro three years ago and I started taking it.
CAPTION:
UP TO 90% OF PEOPLE TAKING MOUNJARO REACHED AN A1C UNDER 7%
CAPTION:
Individual results may vary.
CAPTION:
In studies with or without other diabetes medications, 75% (5mg) to 90% (10mg) of people taking Mounjaro reached an A1C <7%. Average starting A1C was 7.9% to 8.6% across the 5-, 10-, 15-mg doses. In a study of basal insulin with or without Mounjaro, 90% of people taking Mounjaro 10-mg with basal insulin reached A1C <7% vs basal insulin alone.
01:47-01:51
[Discussion continues. Purple bar featuring disclaimers and Mounjaro logo fades out]
ERIC: How does it make you feel to be a part of discovering Mounjaro?
1:52 – 1:57
[Discussion continues. Purple bar displaying disclaimer and Mounjaro logo fades back in ]
TAMER: I’ve seen lots of patients with type 2 diabetes struggle to meet their treatment goals.
CAPTION:
Mounjaro is not a weight-loss drug. Individual results may vary. In studies with or without other diabetes medications, weight loss in adults ranged from 12 lb (5 mg) to 25 lb (15 mg).
01:58-02:06
[Discussion continues.]
TAMER: It’s gratifying to know that Mounjaro, along with diet and exercise, is helping patients lower their A1C. They may lose some weight, too.
CAPTION:
PEOPLE TAKING MOUNJARO LOST UP TO 25 LBS*
CAPTION:
*Mounjaro is not a weight-loss drug. Individual results may vary. In studies with or without other diabetes medications, weight loss in adults ranged from 12 lb (5 mg) to 25 lb (15 mg).
02:06-02:32
[Discussion continues.]
ERIC: Well, I'm so so thankful for it. So, tell me—what excites you most about these innovations?
TAMER: What excites me the most is seeing the impact Mounjaro can make in patients' lives and hopefully give them the ability to help manage and control their blood sugar. The other exciting part is learning from patients' treatment experiences and applying back to science so we can better understand it.
02:33-3:03
[Discussion continues.]
ERIC: So, you’re one of the discovery scientists. But there are so many others involved in the manufacturing process before the Mounjaro pen gets into people’s hands. I’m about to go on the tour and go behind the scenes. So, what will I be seeing?
TAMER: You’re right. So much goes into making this medicine before it gets to people with type 2 diabetes. There is so much detail, I’m excited for you to see, but I don’t want to give too much away.
ERIC: Alright, fair enough.
03:04-03:12
[Discussion continues. Purple bar displaying disclaimer and Mounjaro logo fades back in. ]
ERIC: Well, thank you so much for educating me about Mounjaro. I kinda feel smarter already. Like, I feel like I kinda can now be a scientist.
CAPTION: Continue watching to see Indication and Safety Summary with Warnings.
03:13-03:29
[Discussion continues. Purple bar displaying disclaimer and Mounjaro logo fades out. Eric pulls out a Lilly branded t-shirt. The two exchange signatures.
ERIC: But before I go, because she’s a fan too, would you sign this t-shirt for my mom?
TAMER: Sure, sure, with pleasure.
ERIC: Yeah, awesome. And it’s Jamey. I’ll sign your coat, maybe.
TAMER: Thank you.
ERIC: Thank you.
03:30-03:36
[Footage of Eric touring Lilly facilities runs as the purple bar displaying disclaimer and Mounjaro logo fades back in and the MSR begins.]
NARRATOR: Don't take Mounjaro if you're allergic to it, or if you or someone in your family had medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2.
CAPTION: Don't take Mounjaro if you're allergic to it, or if you or someone in your family had medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2.
03:37-03:43
[Footage of Eric touring Lilly facilities and MSR continue.]
NARRATOR: Stop and call your doctor right away if you have an allergic reaction, a lump or swelling in your neck, severe stomach pain, or vision changes.
CAPTION: Stop and call your doctor right away if you have an allergic reaction, a lump or swelling in your neck, severe stomach pain, or vision changes.
03:44-03:46
[Footage of Eric touring Lilly facilities and MSR continue.]
NARRATOR: Serious side effects may include inflamed pancreas and gallbladder problems.
CAPTION: Serious side effects may include inflamed pancreas and gallbladder problems.
03:47-03:50
[Footage of Eric touring Lilly facilities and MSR continue.]
NARRATOR: Taking Mounjaro with a sulfonylurea or insulin may cause low blood sugar.
CAPTION: Taking Mounjaro with a sulfonylurea or insulin may cause low blood sugar.
03:51-03:56
[Footage of Eric touring Lilly facilities and MSR continue.]
NARRATOR: Tell your doctor if you're nursing, pregnant, plan to be, or taking birth control pills and before scheduled procedures with anesthesia.
CAPTION: Tell your doctor if you're nursing, pregnant, plan to be, or taking birth control pills and before scheduled procedures with anesthesia.
03:57-04:02
[Footage of Eric touring Lilly facilities and MSR continue.]
NARRATOR: Side effects include nausea, diarrhea and vomiting, which can cause dehydration, and may cause kidney problems.
CAPTION: Side effects include nausea, diarrhea and vomiting, which can cause dehydration, and may cause kidney problems.
04:03-04:05
[Footage of Eric touring Lilly facilities and MSR fades out after completion..]
CAPTION: Continue watching to see Indication and Safety Summary with Warnings.
04:06-04:07
[Eric turns to camera.]
ERIC: Yay, science!
04:08-04:14
[Mounjaro logo animation covers the screen.]
CAPTION: Logo, Once weekly Mounjaro
(tirzepatide) injection 0.5 mL
2.5 mg - 5 mg - 7.5 mg - 10 mg - 12.5 mg – 15 mg
A Lilly Medicine
If eligible and commercially insured with coverage for Mounjaro
Pay as little as $25.
CAPTION:
Offer valid for a 1-month or up to 3-month prescription of Mounjaro.
Governmental beneficiaries excluded. Month is defined as 28 days and up to 4 pens. NOT INSURANCE. Card eligibility and terms and conditions apply. Lilly reserves the right to modify or cancel this offer at any time. Review full terms and conditions at https://www.mounjaro.lilly.com/savings-resources#savings.
For more details and pricing information, visit Mounjaro.Lilly.com or call 1-800-545-5979.
04:15-06:04
[Scrolls through CBS.]
CAPTION:
INDICATION AND SAFETY SUMMARY WITH WARNINGS
Mounjaro® (mown-JAHR-OH) is an injectable medicine for adults with type 2 diabetes used along with diet and exercise to improve blood sugar (glucose).
- It is not known if Mounjaro is safe and effective for use in children.
Warnings - Mounjaro may cause tumors in the thyroid, including thyroid cancer. Watch for possible symptoms, such as a lump or swelling in the neck, hoarseness, trouble swallowing, or shortness of breath. If you have any of these symptoms, tell your healthcare provider.
- Do not use Mounjaro if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC).
- Do not use Mounjaro if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
- Do not use Mounjaro if you are allergic to it or any of the ingredients in Mounjaro.
Mounjaro may cause serious side effects, including:
Inflammation of the pancreas (pancreatitis). Stop using Mounjaro and call your healthcare provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without vomiting. You may feel the pain from your abdomen to your back.
Low blood sugar (hypoglycemia). Your risk for getting low blood sugar may be higher if you use Mounjaro with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin. Signs and symptoms of low blood sugar may include dizziness or light-headedness, sweating, confusion or drowsiness, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability, or mood changes, hunger, weakness and feeling jittery.
Serious allergic reactions. Stop using Mounjaro and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue or throat, problems breathing or swallowing, severe rash or itching, fainting or feeling dizzy, and very rapid heartbeat.
Dehydration leading to kidney problems. Diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems. It is important for you to drink fluids to help reduce your chance of dehydration.
Severe stomach problems. Stomach problems, sometimes severe, have been reported in people who use Mounjaro. Tell your healthcare provider if you have stomach problems that are severe or will not go away.
Changes in vision. Tell your healthcare provider if you have changes in vision during treatment with Mounjaro.
Gallbladder problems. Gallbladder problems have happened in some people who use Mounjaro. Tell your healthcare provider right away if you get symptoms of gallbladder problems, which may include pain in your upper stomach (abdomen), fever, yellowing of skin or eyes (jaundice), and clay-colored stools.
Food or liquid getting into the lungs during surgery or other procedures that use anesthesia or deep sleepiness (deep sedation). Mounjaro may increase the chance of food getting into your lungs during surgery or other procedures. Tell all your healthcare providers that you are taking Mounjaro before you are scheduled to have surgery or other procedures.
Common side effects
The most common side effects of Mounjaro include nausea, diarrhea, decreased appetite, vomiting, constipation, indigestion, and stomach (abdominal) pain. These are not all the possible side effects of Mounjaro. Talk to your healthcare provider about any side effect that bothers you or doesn’t go away.
Tell your healthcare provider if you have any side effects. You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch.
Before using Mounjaro
- Your healthcare provider should show you how to use Mounjaro before you use it for the first time.
- Talk to your healthcare provider about low blood sugar and how to manage it.
- If you take birth control pills by mouth, talk to your healthcare provider before you use Mounjaro. Birth control pills may not work as well while using Mounjaro. Your healthcare provider may recommend another type of birth control for 4 weeks after you start Mounjaro and for 4 weeks after each increase in your dose of Mounjaro.
Review these questions with your healthcare provider:
❑ Do you have other medical conditions, including problems with your pancreas, or severe problems with your stomach, such as slowed emptying of your stomach (gastroparesis) or problems digesting food?
❑ Do you take other diabetes medicines, such as insulin or sulfonylureas?
❑ Do you have a history of diabetic retinopathy?
❑ Are you scheduled to have surgery or other procedures that use anesthesia or deep sleepiness (deep sedation)?
❑ Are you pregnant, plan to become pregnant, breastfeeding, or plan to breastfeed? It is not known if Mounjaro will harm your unborn baby or pass into your breast milk.
❑ Do you take any other prescription medicines or over-the-counter drugs, vitamins, or herbal supplements?
How to take
- Read the Instructions for Use that come with Mounjaro.
- Use Mounjaro exactly as your healthcare provider says.
- Inject Mounjaro under the skin (subcutaneously) of your stomach (abdomen), thigh, or upper arm. Do not inject Mounjaro into a muscle (intramuscularly) or vein (intravenously).
- Use Mounjaro 1 time each week, at any time of the day.
- Do not mix insulin and Mounjaro together in the same injection.
- You may give an injection of Mounjaro and insulin in the same body area (such as your stomach area), but not right next to each other.
- Change (rotate) your injection site with each weekly injection. Do not use the same site for each injection.
- If you take too much Mounjaro, call your healthcare provider or Poison Help line at 1-800-222-1222 or go to the nearest hospital emergency room right away.
Learn more
Mounjaro is a prescription medicine available as a pre-filled single-dose pen in 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, or 15 mg per 0.5 mL injection. For more information, call 1-800-LillyRX (800-545-5979) or go to www.mounjaro.lilly.com.
This summary provides basic information about Mounjaro but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your healthcare provider. Be sure to talk to your healthcare provider about Mounjaro and how to take it. Your healthcare provider is the best person to help you decide if Mounjaro is right for you.
TR CON CBS 13JUN2025
Mounjaro® and its delivery device base are registered trademarks owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.
06:05-06:07
[Lilly end frame fades onto screen]
CAPTION: Lilly logo
A MEDICINE COMPANY
PP-TR-US-3272 09/2025 ©Lilly USA, LLC 2025. All rights reserved.
Mounjaro® and its delivery device base are registered trademarks owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.