00:00-00:34
[Captions appear on screen while narrator begins reading the captions. Mounjaro logo appears on screen.]
Narrator: How to use Mounjaro (tirzepatide) injection. Mounjaro is an injectable medicine for adults with type two diabetes, used along with diet and exercise to improve blood sugar or glucose. It is not known if Mounjaro can be used in people who have had inflammation of the pancreas or pancreatitis. Mounjaro is not for use in people with type one diabetes. It is not known if Mounjaro is safe and effective for use in children under 18 years of age. See safety summary, including warnings at the end of this video.
Caption: How to use Mounjaro ( tirzepatide) injection. Mounjaro is an injectable medicine for adults with type two diabetes, used along with diet and exercise to improve blood sugar or glucose. It is not known if Mounjaro can be used in people who have had inflammation of the pancreas or pancreatitis. Mounjaro is not for use in people with type one diabetes. It is not known if Mounjaro is safe and effective for use in children under 18 years of age. See safety summary, including warnings at the end of this video.
00:34-01:01
[Screen transitions to show captions and image of an illustrated refrigerator. The illustration transitions from the refrigerator to a chair and table with a box on it. The illustration transitions to an open box with representation of instructions within the box.]
Narrator: In this video, you will learn how to use the Mounjaro pen. This video is a guide for patients on how to use the Mounjaro pen, based on the instructions for use that come with the Mounjaro pen. Make sure to review the front and back of the Mounjaro carton for important information and safety instructions for this medicine. Carefully read the instructions for use and medication guide that come with your pen before using the Mounjaro pen, and each time you get your refill.
Caption: Getting started with your Mounjaro® pen. Always read the Instructions for Use and the Medication Guide carefully. Please see the instructions for Use and the Medication Guide included with the medication carton and also available on www.mounjaro.lilly.com.
01:01-01:21
[The illustration fades from the screen and transitions to show caption text.]
Narrator: These instructions do not replace the full prescribing information and (IFU) instructions for use that came with your medicine. Please read the full medication guide and IFU carefully. This information does not take the place of talking to your health care provider about your medical condition or treatment.
Caption: Getting started with your Mounjaro® pen. These instructions do not replace the full prescribing information and (IFU) instructions for use that came with your medicine.
Please read the full medication
guide and if you carefully. This information does not take the place of talking to your health care provider about your medical condition or treatment.
0 1:21-01:40
[Screen transitions to show image of the Mounjaro pen with captions identifying the various parts of the pen.]
Narrator: The Mounjaro pen includes features that will be used to help guide you through the injection. The purple injection button. The lock ring. The medicine, which is colorless to slightly yellow. The clear base and the gray base cap. Ready to learn how to use Mounjaro Pen once weekly?
Caption: The Mounjaro® pen. Injection Button. Lock Ring. Medicine. Clear Base. Base Cap. Please note there is a difference in pen color between 2.5, 5, 7.5, 10, 12.5, and 15 mg Mounjaro doses.
01:40-02:13
[Screen transitions to an illustration of an open refrigerator with the Mounjaro carton within. Screen transitions to an image of the Mounjaro pen. Screen transitions to a video of a set of hands doing the motion of washing hands.]
Narrator: Let's begin with preparing for your injection. Remove the carton from the refrigerator. Remove the pen from the carton. Do not remove the gray base cap from the pen. Check the pen label to make sure you have the right medicine and dose, and that it has not expired. Make sure that the pen is not damaged. Make sure the medicine is colorless to slightly yellow. Make sure the medicine is not frozen, not cloudy, and does not have particles in it. Get ready for your injection by washing your hands.
Caption: Preparing for you Mounjaro® injection. Remove the carton from the refrigerator. Check the pen label. Inspect the pen to make sure that it is not damaged. The medicine should be colorless to slightly yellow. The medicine should not be frozen, not cloudy, and should not have particles in it.
02:13-02:28
[Screen transitions to white background with Mounjaro logo and caption text.]
Narrator: We will now review the four steps to inject your dose of Mounjaro.
Caption: 4 STEPS TO USE YOUR MOUNJARO PEN. These are not the complete instructions for using Moujaro. Before starting Mounjaro, your healthcare provider should show you how to use the pen. Read the Instructions for Use included with your pen or watch how to use the Mounjaro pen at www.mounjaro.lilly.com.
02:28-02:48
[Screen transitions to illustration of the human body and highlights areas on the body in purple to show injection sites. Different highlighted areas on the body illuminate one at a time to represent changing the injection site each week.]
Narrator: Step one: Choose your injection site. You can inject the medicine in your stomach or thigh, or you can have another person give you the injection in the back of your upper arm. Change or rotate your injection site each week. You may use the same area of your body, but be sure to choose a different injection site in that area.
Caption: Step 1 – Choose your injection site. Someone else can give you the injection in the back of your upper arm. Change (rotate) your injection site each week.
02:48-02:13
[Screen transitions to show an illustration representing how to pull off the gray cap from the Mounjaro pen.]
Narrator: Step two: Pull off the gray base cap. Make sure the pen is locked. Do not unlock the pen. Pull the gray base cap straight off. Throw away the gray base cap in your household trash. Do not put the gray base cap back on. This could damage the needle. Do not touch the needle.
Caption: Step 2 – Pull off the gray base cap. Make sure the pen is locked. Do not unlock the pen. Pull off gray base cap. Do not put the gray base cap back on.
03:13-03:30
[Screen transitions to show an illustration representing how to place the clear base on skin and how to unlock the Mounjaro pen.]
Narrator: Step three. Place clear base on the skin, then unlock. Place the clear base flat against your skin at the injection site you've chosen. When the clear base is flat against your skin, unlock the pen by turning the lock ring.
Caption: Step 3 – Place clear base on skin, then unlock. Place the clear base flat against your skin at the injection site. Unlock the pen by turning the lock ring.
03:30-03:56
[Screen transitions to show an illustration representing how to press and hold the purple injection button on the Mounjaro pen.]
Narrator: Step four: Press and hold up to 10 seconds. Press and hold the purple injection button. Listen for the first click which indicates the injection has started. Continue to hold the purple injection button until you hear the second click, which indicates that the injection is completed. You'll know your injection is complete when the gray plunger is visible. Remove the pen from your skin.
Caption: Step 4 – Press and hold up to 10 seconds. Press and hold the purple injection button. Listen for the first click. Listen for the second click. The injection is complete when the gray plunger is visible. Remove the pen from your skin.
03:56-04:42
[Screen transitions to illustration representing proper disposal of Mounjaro pen in a sharps disposal container.]
Narrator: Disposing of your used pen right after your injection. Place your use pen in a sharps disposal container. Do not throw away pens in your household trash. If you do not have a sharps disposal container, you may use a household container that is made of a heavy-duty plastic. Can be closed with a tight fitting, puncture resistant lid without sharps being able to come out. Upright and stable during use. Leak resistant and properly label to warn of hazardous waste inside the container. Do not recycle your use sharps disposal container. Ask your health care provider or follow the community guidelines in your area on how to properly dispose of your sharps disposal container.
Caption: Disposing of your used pen. Put your used pen is a sharps disposal container. Do not throw away pens in your household trash. If you do not have a sharps disposal container, you may use a household container that is: Made of a heavy-duty plastic, can be closed with a tight-fitting, puncture resistant lid, without sharps being able to come out, upright and stable during use, leak-resistant, properly labelled to warn of hazardous waste inside container. Do not recycle your used sharps disposal container.
04:42-05:04
[Screen transitions to white background with caption text.]
Narrator: It is important that you learn how to properly store and handle the Mounjaro pen. Some important reminders include: Store your pen in the refrigerator. Do not freeze your pen. Store your pen in the original carton to protect from light. Please read the storage and handling instructions that come with your pen for additional information.
Caption: Storage and handling. Story your pen in the refrigerator between 36°F to 46°F (2°C to 8°C). You may store your pen at room temperature below 86°F (30°C) for yup to a total of 21 days. Do not freeze your pen. If the pen has been frozen, throw the pen away and use a new pen. Store your pen in the original carton to protect your pen from light. The pen has glass parts. Handle it carefully. If you drop the pen on a hard surface, do not use it. Use a new pen for your injection. Keep your Mounjaro® pen and all medicine out of the sight and reach of children. This video is based on the Mounjaro® Instructions for Use that come with your Mounjaro® pen. Always read the Instructions for Use and the Medication Guide carefully before using your Mounjaro® Pen and each time you get a refill.
05:04-05:13
[Screen transitions to white background with caption text.]
Narrator: If you have any questions or concerns about administering Mounjaro, please contact your health care provider or Lilly.
Caption: If you have any questions about injecting Mounjaro® or problems with your Mounjaro® pen, contact your healthcare provider or Lilly. For more information about the Mounjaro® pen, visit our website at www.mounjaro.lilly.com.
05:13-05:41
[Screen transitions to the Mounjaro Indication and Safety Summary with Warnings as the narrator begins reading the text on screen. The text begins to slowly scroll.]
Narrator: Indication and safety summary with warnings. Mounjaro is an injectable medicine for adults with type 2 diabetes used along with diet and exercise to improve blood sugar (glucose).
It is not known if Mounjaro can be used in people who have had inflammation of the pancreas (pancreatitis). Mounjaro is not for use in people with type 1 diabetes. It is not known if Mounjaro is safe and effective for use in children under 18 years of age.
05:41-06:18
[Text scrolls as narrator continues reading.]
Narrator: Warnings. Mounjaro may cause tumors in the thyroid, including thyroid cancer. Watch for possible symptoms, such as a lump or swelling in the neck, hoarseness, trouble swallowing, or shortness of breath. If you have any of these symptoms, tell your healthcare provider.
Do not use Mounjaro if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC). Do not use Mounjaro if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Do not use Mounjaro if you are allergic to it or any of the ingredients in Mounjaro.
06:18-06:36
[Text scrolls as narrator continues reading.]
Narrator: Mounjaro may cause serious side effects, including: Inflammation of the pancreas (pancreatitis). Stop using Mounjaro and call your healthcare provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without vomiting. You may feel the pain from your abdomen to your back.
06:36-07:08
[Text scrolls as narrator continues reading.]
Narrator: Low blood sugar (hypoglycemia). Your risk for getting low blood sugar may be higher if you use Mounjaro with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin. Signs and symptoms of low blood sugar may include dizziness or light-headedness, sweating, confusion or drowsiness, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability, or mood changes, hunger, weakness and feeling jittery.
07:08-07:27
[Text scrolls as narrator continues reading.]
Narrator: Serious allergic reactions. Stop using Mounjaro and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue or throat, problems breathing or swallowing, severe rash or itching, fainting or feeling dizzy, and very rapid heartbeat.
07:08-07:44
[Text scrolls as narrator continues reading.]
Narrator: Kidney problems (kidney failure). In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems to get worse. It is important for you to drink fluids to help reduce your chance of dehydration.
07:44-07:56
[Text scrolls as narrator continues reading.]
Narrator: Severe stomach problems. Stomach problems, sometimes severe, have been reported in people who use Mounjaro. Tell your healthcare provider if you have stomach problems that are severe or will not go away.
07:56-08:03
[Text scrolls as narrator continues reading.]
Narrator: Changes in vision. Tell your healthcare provider if you have changes in vision during treatment with Mounjaro.
08:03-08:21
[Text scrolls as narrator continues reading.]
Narrator: Gallbladder problems. Gallbladder problems have happened in some people who use Mounjaro. Tell your healthcare provider right away if you get symptoms of gallbladder problems, which may include pain in your upper stomach (abdomen), fever, yellowing of skin or eyes (jaundice), and clay-colored stools.
08:21-08:41
[Text scrolls as narrator continues reading.]
Narrator: Food or liquid getting into the lungs during surgery or other procedures that use anesthesia or deep sleepiness (deep sedation). Mounjaro may increase the chance of food getting into your lungs during surgery or other procedures. Tell all your healthcare providers that you are taking Mounjaro before you are scheduled to have surgery or other procedures.
08:41-09:16
[Text scrolls as narrator continues reading.]
Narrator: Common side effects. The most common side effects of Mounjaro include nausea, diarrhea, decreased appetite, vomiting, constipation, indigestion, and stomach (abdominal) pain. These are not all the possible side effects of Mounjaro. Talk to your healthcare provider about any side effect that bothers you or doesn’t go away.
Tell your healthcare provider if you have any side effects. You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch.
09:16-09:46
[Text scrolls as narrator continues reading.]
Narrator: Before using Mounjaro. Your healthcare provider should show you how to use Mounjaro before you use it for the first time. Talk to your healthcare provider about low blood sugar and how to manage it. If you take birth control pills by mouth, talk to your healthcare provider before you use Mounjaro. Birth control pills may not work as well while using Mounjaro. Your healthcare provider may recommend another type of birth control for 4 weeks after you start Mounjaro and for 4 weeks after each increase in your dose of Mounjaro.
09:46-10:29
[Text scrolls as narrator continues reading.]
Narrator: Review these questions with your healthcare provider:
Do you have other medical conditions, including problems with your pancreas or kidneys, or severe problems with your stomach, such as slowed emptying of your stomach (gastroparesis) or problems digesting food?
Do you take other diabetes medicines, such as insulin or sulfonylureas?
Do you have a history of diabetic retinopathy?
Are you scheduled to have surgery or other procedures that use anesthesia or deep sleepiness (deep sedation)?
Are you pregnant, plan to become pregnant, breastfeeding, or plan to breastfeed? It is not known if Mounjaro will harm your unborn baby or pass into your breast milk.
Do you take any other prescription medicines or over-the-counter drugs, vitamins, or herbal supplements?
10:29-11:13
[Text scrolls as narrator continues reading.]
Narrator: How to take. Read the Instructions for Use that come with Mounjaro. Use Mounjaro exactly as your healthcare provider says. Mounjaro is injected under the skin (subcutaneously) of your stomach (abdomen), thigh, or upper arm. Use Mounjaro 1 time each week, at any time of the day. Do not mix insulin and Mounjaro together in the same injection. You may give an injection of Mounjaro and insulin in the same body area (such as your stomach area), but not right next to each other. Change (rotate) your injection site with each weekly injection. Do not use the same site for each injection. If you take too much Mounjaro, call your healthcare provider or seek medical advice promptly.
11:13-12:08
[Text scrolls as narrator continues reading.]
Narrator: Learn more. Mounjaro is a prescription medicine available as a pre-filled single-dose pen in 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, or 15 mg per 0.5 mL injection. For more information, call 1-833-807-MJRO (833-807-6576) or go to www.mounjaro.lilly.com.
This summary provides basic information about Mounjaro but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your healthcare provider. Be sure to talk to your healthcare provider about Mounjaro and how to take it. Your healthcare provider is the best person to help you decide if Mounjaro is right for you.
Caption: TR CON CBS 05NOV2024
Mounjaro® and its delivery device base are registered trademarks owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.
12:08-12:16
[Text fades away and transitions to the Mounjaro logo and Lilly logo on a white background.]
Caption: Once weekly Mounjaro (tirzepatide) injection
A Lilly Medicine
Mounjaro® and its delivery device base are registered trademarks owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.
PP-TR-US-2350 01/2025
©Lilly USA, LLC 2025. All rights reserved.