Post Hoc Analysis: Mean weight change from baseline (40 weeks)11
Patients With Baseline BMI <30 kg/m2
Bar graph showing the absolute and percentage mean weight change in patients with a baseline BMI of <30 kg/m2 at 40 weeks in the SURPASS-2 trial (Mounjaro 5 mg, 10 mg, and 15 mg vs Ozempic 1 mg). Mean changes were -11.9 lb (-7.2%) for Mounjaro 5 mg (n=140), -15.9 lb (-9.4%) for Mounjaro 10 mg (n=133), -17.4 lb (-10.6%) for Mounjaro 15 mg (n=134), and -10.8 lb (-6.6%) for Ozempic 1 mg (n=144) from mean baseline weights of 165.1 lb, 167.6 lb, 164.9 lb, and 170.0 lb, respectively.
Patients with baseline BMI ≥30 kg/m2:
The mean weight change of patients with a baseline BMI of ≥30 kg/m2 was -18.7 lb (-8.6%) for Mounjaro 5 mg (n=330), -22.5 lb (-10.3%) for Mounjaro 10 mg (n=336), and -27.6 lb (-12.3%) for Mounjaro 15 mg (n=335) vs -13.2 lb (-6.1%) for Ozempic 1 mg (n=324) from mean baseline weights of 220.2 lb, 225.5 lb, 223.5 lb, and 222.9 lb, respectively.