A line graph that shows the mean A1C for Mounjaro 15 mg or maximum tolerated dose plus metformin and for intensified conventional care plus metformin from baseline to 104 weeks. 383 patients took Mounjaro 15 mg or maximum tolerated dose plus metformin, and 385 patients underwent intensified conventional care plus metformin. At the start of treatment, both treatment groups had a mean baseline A1C of 7.8%.
At the primary endpoint (104 weeks), patients taking Mounjaro 15 mg or maximum tolerated dose plus metformin had a mean change in A1C of -2.0% and a final mean of 5.6%, and patients undergoing intensified conventional care plus metformin had a mean change in A1C of -1.3% and a final mean of 6.4%.