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How to use Mounjaro

See how to use Mounjaro

Get all of the details in our video below and in the Instructions for Use.

Easy to use no disclaimer

*Before using the Mounjaro Pen, read the accompanying Instructions for Use (IFU) or watch how to use the Mounjaro Pen at www.mounjaro.lilly.com. In a study of adults with type 2 diabetes for another medicine that uses the same single-dose pen as Mounjaro, 99% said that, after adequate training, the single-dose pen was easy to use. Instructions for Use for the Mounjaro single-dose pen differ from the Instructions for Use provided in the study.

Calendar showing reminders for once-weekly injection

Take Mounjaro once a week

Pick your day.

Use Mounjaro 1 time each week, at any time of the day.

But we know schedules can change. If you want to change the day of the week you take your dose, make sure there are at least 3 days (72 hours) between doses.

If you miss a dose of Mounjaro, take the missed dose as soon as possible within 4 days (96 hours) after the missed dose. If more than 4 days have passed, skip the missed dose and take your next dose on the regularly scheduled day. Do not take 2 doses of Mounjaro within 3 days of each other.

It may be helpful to set a reminder in your phone so you don't forget which day is your Mounjaro day. If you set a reminder and decide to change your day, then don't forget to update your reminder to your new day.

Mounjaro comes in a single-dose pen that requires no mixing.

There is no need to see or handle the needle.

Read the Instructions for Use included with your pen.

Follow these 4 steps to use your Mounjaro pen:

Mounjaro injection sites on the body

Choose your injection site. Your healthcare provider can help you choose the injection site that is best for you. You or another person can inject the medicine in your stomach (abdomen) or thigh. Another person should give you the injection in the back of your upper arm.

how to inject mounjaro step 2

Pull off the base cap.

How to inject mounjaro step 3

Place the base flat on your skin, then unlock.

How to inject mounjaro step 4

Press and hold the button for up to 10 seconds. Listen for the first click. It means the injection has started. The second click means that the injection is complete.

These are not the complete instructions for using Mounjaro. Before starting Mounjaro, your healthcare provider should show you how to use the pen. Read the Instructions for Use included with your pen.

Select Safety Information

Gallbladder problems. Gallbladder problems have happened in some people who use Mounjaro. Tell your healthcare provider right away if you get symptoms of gallbladder problems, which may include pain in your upper stomach (abdomen), fever, yellowing of skin or eyes (jaundice), and clay-colored stools.

How to store your Mounjaro pens

Keep Mounjaro in the refrigerator

  • Make sure the temperature is between 36°F to 46°F (2°C to 8°C)
  • Store the pens in the original packaging to protect your pen from light
  • Do not freeze the Mounjaro pens
  • The pen has glass parts. Handle it carefully. If you drop the pen on a hard surface, do not use it. Use a new pen for your injection
  • Keep in mind, some refrigerators can be colder near the back than on the front/on the door
  • Always check your pen to ensure it's not frozen before using it

Going on a trip?

Mounjaro can last unrefrigerated for up to 21 days. Just make sure the temperature does not get any higher than 86°F (30°C). Keep your pen in its original carton to protect your pen from light.

sharps container and disposal of mounjaro

How to dispose of your used Mounjaro pens

It is important to dispose of your pens safely. To do this, put your pen in an FDA-cleared sharps disposal container right away after use. Do not throw away pens in household trash. If you don't have an FDA-approved sharps container, use a household container. Make sure it is made of heavy-duty plastic with a puncture-resistant lid, and it is upright, stable, leak resistant, and properly labeled to warn of hazardous waste.

Keep the container out of the reach of children. Do not recycle your sharps container, follow your community guidelines for the right way to dispose of your sharps disposal container.

Want to know how Mounjaro can help you manage type 2 diabetes?

What is Mounjaro?

Mounjaro is an injectable prescription medicine that is used along with diet and exercise to improve blood sugar (glucose) in adults with type 2 diabetes mellitus.

It is not known if Mounjaro can be used in people who have had pancreatitis. Mounjaro is not for use in people with type 1 diabetes. It is not known if Mounjaro is safe and effective for use in children under 18 years of age.

Once-weekly Mounjaro has multiple dose options

Mounjaro has different dose options, allowing you and your doctor to find the one that's right for you. If your doctor has prescribed once-weekly Mounjaro, you'll start with 2.5 mg. After 4 weeks, you'll move on to 5 mg.§

§Mounjaro should be used once every week. Please consult your doctor with any questions you may have about your Mounjaro prescription.

Start and continue Mounjaro dosing

What happens next?

Let your doctor know how you're doing on the 2.5-mg and 5-mg doses during your checkup. Once you reach 5 mg, your doctor may keep you at the same dose for longer than 4 weeks. You'll work together to decide if your dose needs to be increased beyond 5 mg.

Tip: Set a reminder to make sure you pick up your next dose

Managing possible side effects

Talk to your doctor if you have any side effect that bothers you or does not go away.

Everyone can have a different experience, but here are the most common side effects experienced by patients taking Mounjaro:

  • Nausea
  • Diarrhea
  • Decreased appetite
  • Vomiting
  • Constipation
  • Indigestion
  • Stomach Pain

In studies, most nausea, vomiting and diarrhea events occurred while the dose of Mounjaro was being increased. These events decreased over time.

In studies, GI side effects were more common in people taking Mounjaro than people taking placebo, and people taking Mounjaro were more likely to stop treatment because of these side effects.

Select Safety Information

Kidney problems (kidney failure). In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems to get worse. It is important for you to drink fluids to help reduce your chance of dehydration.

Severe stomach problems. Stomach problems, sometimes severe, have been reported with Mounjaro. Tell your health care provider if you have stomach problems that are severe or will not go away.

If you experience nausea, talk to your doctor. In the meantime, some people find the following tips may help:

smaller, more frequent, meals icon

Eat smaller meals–try splitting your 3 daily meals into 4 or more smaller ones

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Stop eating when you feel full

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Avoid fat or fatty foods

bland food icon

Try eating bland foods like toast, crackers, or rice

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Questions? Call us.

We know we can't replace the advice of your doctor, but we are here to help any way we can.

If you have additional questions, call us at 1-833-807-MJRO (833-807-6576).

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Mounjaro Savings

We want to help. You may pay as little as $25 for a 1-month or 3-month prescription with the Mounjaro Savings Card.* †

*For eligible commercially insured patients with Mounjaro coverage. Governmental beneficiaries excluded, terms and conditions apply.

One month is defined as 28 days and 4 pens. Three months is defined as 84 days and up to 12 pens.

By enrolling in and using the Mounjaro Savings Card Program ("Program") and using the Mounjaro Savings Card ("Card"), you attest that you meet the eligibility criteria, and you agree to comply with the terms and conditions described below:

Card Eligibility:

  1. You have been prescribed Mounjaro for an approved use consistent with FDA approved product labeling;
  2. You are enrolled in a commercial drug insurance plan;
  3. You are not enrolled in any state, federal, or government funded healthcare program, including, without limitation, Medicaid, Medicare, Medicare Part D, Medicare Advantage, Medigap, DoD, VA, TRICARE®/CHAMPUS, or any state prescription drug assistance program;
  4. You are a resident of the United States or Puerto Rico; and
  5. You are 18 years of age or older.

Card Terms and Conditions

For patients with commercial drug insurance coverage for Mounjaro: You must have commercial drug insurance that covers Mounjaro®(tirzepatide) and a prescription for an approved use consistent with FDA-approved product labeling to pay as little as $25 for a 1-month, 2-month, or 3-month prescription fill of Mounjaro. One month is defined as 28-days and up to 4 pens; 2 months is defined as 56 days and up to 8 pens; 3 months is defined as 84 days and up to 12 pens. Card savings are subject to a maximum monthly savings of up to $150 per 1-month prescription, $300 per 2-month prescription, or $450 per 3-month prescription fill and separate maximum annual savings of up to $1,950 per calendar year. Card may be used for a maximum of up to 13 prescription fills per calendar year. Participation in the Program requires a valid patient HIPAA authorization. Subject to Lilly USA, LLC's ("Lilly") right to terminate, rescind, revoke, or amend Card eligibility criteria and/or Card terms and conditions which may occur at Lilly's sole discretion, without notice, and for any reason. Card expires and savings end on 12/31/2025.

For patients with commercial drug insurance who do not have coverage for Mounjaro: You must have commercial drug insurance that does not cover Mounjaro and a prescription for an approved use consistent with FDA-approved product labeling to obtain savings of up to $473 off your 1-month prescription fill of Mounjaro. Month is defined as 28-days and up to 4 pens. Card savings are subject to a maximum monthly savings of up to $473 and a separate maximum annual savings of up to $3,311 per calendar year. Card may be used for a maximum of up to 7 prescription fills per calendar year. Participation in the Program requires a valid patient HIPAA authorization. Subject to Lilly's right to terminate, rescind, revoke, or amend Card eligibility criteria and/or Card terms and conditions which may occur at Lilly's sole discretion, without notice, and for any reason. Card expires and savings end on 06/30/2025.

Additional Terms and Conditions

If you have an insurance plan that is participating in an alternate funding program ("AFP") that requires you to apply to the Mounjaro Savings Card Program or otherwise pursue specialty drug prescription coverage through an alternate funding vendor as a condition of, requirement for, or prerequisite to coverage of Mounjaro, you are not eligible for and are prohibited from using the Mounjaro Savings Card Program. AFPs include programs where coverage, reimbursement, or patient out of pocket costs for a product in some way vary based on the availability of a manufacturer co-pay program. AFPs may modify, delay, deny, restrict, or withhold insurance benefits or coverage from patients, or exclude Lilly products from coverage contingent upon a member's use of Mounjaro Savings Card Program. You agree to inform the Mounjaro Savings Card Program if you are or become a member of such an alternative funding program. You are responsible for any applicable taxes, fees, and any amount that exceeds the applicable monthly or annual maximum Card savings. Monthly and annual maximum savings are set at Lilly's sole and absolute discretion and may be changed with or without notice at any time for any reason. At its sole discretion and with or without notice, Lilly may reduce, eliminate, or otherwise modify the Card savings for any reason, including but not limited to if your commercial drug insurance plan imposes additional requirements which limits or prevents you from receiving coverage for Mounjaro, only allows partial coverage for Mounjaro, removes coverage for Mounjaro and requires you to utilize the Card, does not provide a material level of financial assistance for the cost of Mounjaro, or does not apply Card payments to satisfy your co-payment, deductible, or coinsurance for Mounjaro. Card savings are not valid for: Massachusetts residents if an AB-rated generic equivalent is available; California residents if an FDA-approved therapeutic equivalent is available. You must meet the Card eligibility criteria, terms and conditions every time you use the Card. If at any time you begin receiving drug coverage under any state, federal, or government funded healthcare program, you understand that you will no longer be eligible for the Mounjaro Savings Card and agree to call the Mounjaro Savings Card Program at 1-844-805-5807 to stop participation. Card activation is required. You may not seek reimbursement from your health insurance, any third party, or any health savings, flexible spending, or other healthcare reimbursement accounts, for any amount of the savings received through the Card. By utilizing the Card, you agree that if you are required to do so under the terms of your insurance coverage for this prescription or are otherwise required to do so by law, you will notify your Insurance Carrier of your redemption of the Card. Card savings cannot be combined or utilized with any other program, discount, discount card, cash discount card, coupon, incentive, or similar offer involving Mounjaro. You agree that this Card savings is intended solely for the benefit of you, the patient, and that the Card benefits are nontransferable. It is prohibited for any person to sell, purchase, or trade; or to offer to sell, purchase, or trade, or to counterfeit the Card. THIS CARD IS NOT INSURANCE. Lilly has the sole right to interpret and apply Card eligibility criteria, and terms and conditions. Card eligibility, and terms and conditions may be terminated, rescinded, revoked, or amended by Lilly at any time without notice and for any reason. Lilly's sole discretion to terminate, rescind, revoke, or amend Card eligibility criteria and/or Card terms and conditions includes the right to terminate any individual Card if Lilly determines, in its sole discretion, that a patient does not satisfy the Card's eligibility criteria or is using or has attempted to use the Card inconsistently with these terms and conditions. Eligibility criteria, and terms and conditions for the Mounjaro Savings Card Program may change from time to time; the most current version can be found at https://www.mounjaro.lilly.com/savings-resources#savings. You may be required to obtain a new Card, including if any Card terms and conditions have been terminated, rescinded, revoked, or amended by Lilly. Card void where prohibited by law. Subject to Lilly's right to terminate, rescind, revoke, or amend Card eligibility criteria and/or Card terms and conditions which may occur at Lilly's sole discretion, without notice, and for any reason. Card expires and savings end on 12/31/2025 for patients with commercial drug insurance with coverage for Mounjaro and on 06/30/2025 for patients with commercial drug insurance who do not have coverage for Mounjaro.

INDICATION

Mounjaro® (mown-JAHR-OH) is an injectable medicine for adults with type 2 diabetes used along with diet and exercise to improve blood sugar (glucose).

  • It is not known if Mounjaro can be used in people who have had inflammation of the pancreas (pancreatitis). Mounjaro is not for use in people with type 1 diabetes. It is not known if Mounjaro is safe and effective for use in children under 18 years of age.

SAFETY SUMMARY WITH WARNINGS

Warnings -

Mounjaro may cause tumors in the thyroid, including thyroid cancer. Watch for possible symptoms, such as a lump or swelling in the neck, hoarseness, trouble swallowing, or shortness of breath. If you have any of these symptoms, tell your healthcare provider.

  • Do not use Mounjaro if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC).
  • Do not use Mounjaro if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
  • Do not use Mounjaro if you are allergic to it or any of the ingredients in Mounjaro.

Mounjaro may cause serious side effects, including:

Inflammation of the pancreas (pancreatitis). Stop using Mounjaro and call your healthcare provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without vomiting. You may feel the pain from your abdomen to your back.

Low blood sugar (hypoglycemia). Your risk for getting low blood sugar may be higher if you use Mounjaro with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin. Signs and symptoms of low blood sugar may include dizziness or light-headedness, sweating, confusion or drowsiness, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability, or mood changes, hunger, weakness and feeling jittery.

Serious allergic reactions. Stop using Mounjaro and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue or throat, problems breathing or swallowing, severe rash or itching, fainting or feeling dizzy, and very rapid heartbeat.

Kidney problems (kidney failure). In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems to get worse. It is important for you to drink fluids to help reduce your chance of dehydration.

Severe stomach problems. Stomach problems, sometimes severe, have been reported in people who use Mounjaro. Tell your healthcare provider if you have stomach problems that are severe or will not go away.

Changes in vision. Tell your healthcare provider if you have changes in vision during treatment with Mounjaro.

Gallbladder problems. Gallbladder problems have happened in some people who use Mounjaro. Tell your healthcare provider right away if you get symptoms of gallbladder problems, which may include pain in your upper stomach (abdomen), fever, yellowing of skin or eyes (jaundice), and clay-colored stools.

Common side effects

The most common side effects of Mounjaro include nausea, diarrhea, decreased appetite, vomiting, constipation, indigestion, and stomach (abdominal) pain. These are not all the possible side effects of Mounjaro. Talk to your healthcare provider about any side effect that bothers you or doesn't go away.

Tell your healthcare provider if you have any side effects. You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch.

Before using Mounjaro

  • Your healthcare provider should show you how to use Mounjaro before you use it for the first time.
  • Talk to your healthcare provider about low blood sugar and how to manage it.
  • If you take birth control pills by mouth, talk to your healthcare provider before you use Mounjaro. Birth control pills may not work as well while using Mounjaro. Your healthcare provider may recommend another type of birth control for 4 weeks after you start Mounjaro and for 4 weeks after each increase in your dose of Mounjaro.

Review these questions with your healthcare provider:

  • Do you have other medical conditions, including problems with your pancreas or kidneys, or severe problems with your stomach, such as slowed emptying of your stomach (gastroparesis) or problems digesting food?
  • Do you take other diabetes medicines, such as insulin or sulfonylureas?
  • Do you have a history of diabetic retinopathy?
  • Are you pregnant, plan to become pregnant, breastfeeding, or plan to breastfeed? It is not known if Mounjaro will harm your unborn baby or pass into your breast milk.
  • Do you take any other prescription medicines or over-the-counter drugs, vitamins, or herbal supplements?

How to take

  • Read the Instructions for Use that come with Mounjaro.
  • Use Mounjaro exactly as your healthcare provider says.
  • Mounjaro is injected under the skin (subcutaneously) of your stomach (abdomen), thigh, or upper arm.
  • Use Mounjaro 1 time each week, at any time of the day.
  • Do not mix insulin and Mounjaro together in the same injection.
  • You may give an injection of Mounjaro and insulin in the same body area (such as your stomach area), but not right next to each other.
  • Change (rotate) your injection site with each weekly injection. Do not use the same site for each injection.
  • If you take too much Mounjaro, call your healthcare provider or seek medical advice promptly.

Learn more

Mounjaro is a prescription medicine. For more information, call 1-833-807-MJRO (833-807-6576) or go to www.mounjaro.lilly.com.

This summary provides basic information about Mounjaro but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your healthcare provider. Be sure to talk to your healthcare provider about Mounjaro and how to take it. Your healthcare provider is the best person to help you decide if Mounjaro is right for you.

TR CON CBS 14SEP2022

Mounjaro® and its delivery device base are registered trademarks owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.